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June 1975

Single Umbilical Artery: Correlation of Clinical Status and Umbilical Cord Histology

Author Affiliations

From the departments of pediatrics, Cincinnati General Hospital, Cincinnati Children's Hospital, and University of Cincinnati Medical Center (Drs. Altshuler and Tsang); and pathology, Cincinnati General Hospital (Drs. Altshuler and Ermocilla), Cincinnati Children's Hospital (Dr. Altshuler), and University of Cincinnati Medical Center (Drs. Altshuler, Tsang, and Ermocilla).

Am J Dis Child. 1975;129(6):697-700. doi:10.1001/archpedi.1975.02120430037010

Although numerous reports are available concerning infants who have single umbilical artery, there are no studies that correlate the incidence of congenital malformations or prognosis of such infants with the presence or absence of an atrophied artery in their associated umbilical cords. For this reason, we studied 48 infants who have single umbilical artery. No significant differences were detected in congenital malformations or neonatal mortality between infants with atrophy of one of their arteries and infants with arterial aplasia.