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August 1975

Idiopathic Acute Pancreatitis in Children

Author Affiliations

Department of Pediatrics University of Oregon Health Sciences Center Portland, OR 97201

Am J Dis Child. 1975;129(8):984. doi:10.1001/archpedi.1975.02120450086022

Sir.—Morens et al reported two cases of Reye syndrome with acute pancreatitis in the September issue of the Journal (128:401, 1974). They stated that "... pancreatitis has not been described previously in association with this syndrome...." It should be brought to the attention of the readers that Glick et al found pancreatitis in four of 46 necropsies of children with Reye syndrome.1 Review of English literature disclosed ten additional cases with clinical and pathologic features of Reye syndrome in which acute pancreatitis was found at necropsy.2-6 The fact that at least 16 patients have been described so far implies that pancreatitis may be a more common feature of Reye syndrome than previously considered.

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