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August 1975

A Study on the Origins of Mental Retardation

Author Affiliations

Department of Pediatrics University of Rochester Medical Center 260 Crittenden Blvd Rochester, NY 14642

Am J Dis Child. 1975;129(8):987. doi:10.1001/archpedi.1975.02120450089028

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This volume in the Clinics in Developmental Medicine series represents the findings of a meticulous neuroradiological study dealing with the cause of mental retardation.

The subject matter, presentation format, and research design would be of interest to neurologist, pediatrician, internist, radiologist, and any serious public health professional.

A broad-spectrum literature review is presented to cite previous etiological studies on mental retardation, with a focus on other than neuroradiological expertise (sociological, clinical, biochemical, neurophysiological, cytogenetic, and pathological). A review of the literature dealing with previous neuroradiological studies is also provided.

The study was motivated by the belief that treatment and prophylaxis in mental retardation depend on an understanding of the cause and clinical signs.

One thousand patients admitted consecutively to a Finnish mental retardation facility during a 23-year period comprised the study population. All survivors as of Dec 31, 1966, were followed up through physical, cytogenetical, electroencephalographic, and echoencephalographic examinations. A

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