• A 2-year-old boy had a fatal disseminated BCG infection. Immunologic assessment showed a normal humoral response and normal numbers of E rosettes, normal thymus weight and histological features, but an abnormal response of lymphocytes in vitro and negative skin tests. Histological examination showed the presence of Gram-negative acid-fast bacilli within the macrophages. The possible mechanisms of immunodeficiency in this patient are discussed.
(Am J Dis Child 130:433-436, 1976)
Passwell J, Katz D, Frank Y, Spirer Z, Cohen BE, Ziprkowski M. Fatal Disseminated BCG Infection: An Investigation of the Immunodeficiency. Am J Dis Child. 1976;130(4):433–436. doi:10.1001/archpedi.1976.02120050091018
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