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August 1976

A Test for Abnormal Hemoglobins in Umbilical Cord Blood

Author Affiliations

From the Department of Pediatrics, Baylor College of Medicine, and the Research Hematology Laboratory, Texas Children's Hospital, Houston.

Am J Dis Child. 1976;130(8):805-806. doi:10.1001/archpedi.1976.02120090015003

• This article describes a rapid, simple, and inexpensive method for testing the cord blood of infants for the common hemoglobinopathies by electrophoresis using cellulose polycetate strips. In a study of 7,500 umbilical cord blood specimens, 11% were found to contain an abnormal hemoglobin. While the importance of evaluating cord blood in a screening program for hemoglobinopathies is evident, the procedure must be accurate, verified, and followed by proper counseling.

(Am J Dis Child 130:805-806, 1976)