• Elevated serum uric acid concentrations were found in 18 children with hemolytic-uremic syndrome. The highest recorded level in each patient ranged from 10 to 29 mg/100 ml, and nine patients had concentrations of greater than 20 mg/100 ml. During a 53-hour period of peritoneal dialysis, 5.5 gm of uric acid was removed from one infant. Although acute renal failure was probably the major factor, erythrocyte destruction and hyperlacticacidemia may also have been important in the pathogenesis of the hyperuricemia.
(Am J Dis Child 130:854-856, 1976)
Kaplan BS, Thomson PD. Hyperuricemia in the Hemolytic-Uremic Syndrome. Am J Dis Child. 1976;130(8):854–856. doi:10.1001/archpedi.1976.02120090064011
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: