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January 1977

Test Strip Meconium Screening for Cystic Fibrosis

Author Affiliations

From the Department of Pediatrics, The Medical College of Wisconsin, Milwaukee Children's Hospital.

Am J Dis Child. 1977;131(1):71-73. doi:10.1001/archpedi.1977.02120140073013

• The Boehringer-Mannheim Corporation (BMC) strip test is extremely reliable in indicating an albumin content above 20 mg/gm of dried meconium. All infants born during one year in 14 Milwaukee area hospitals were tested. Of 16,224 newborns, two were diagnosed correctly as suffering from cystic fibrosis and two were missed. False-positive tests were obtained in 0.9% of infants (prematurity, melena, gastroschisis, and intrauterine infection). The strip test is, at present, the best available but not the perfect screening method for cystic fibrosis.

(Am J Dis Child 131:71-73, 1977)