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February 1977

Respiratory Syncytial Virus in Early Infancy: Circulating Antibody and the Severity of Infection

Author Affiliations

From the Departments of Pediatrics and Health and Hospitals, the University of Colorado Medical Center, Denver.

Am J Dis Child. 1977;131(2):145-148. doi:10.1001/archpedi.1977.02120150027004

• Forty-one children less than 6 months of age from whom respiratory syncytial virus (RSV) was isolated were divided into groups of varying severity of illness. No relationship was demonstrated between severity of illness and the complement fixation titer to RSV in cord sera, acute sera, or convalescent sera. An increase in lgM level of ≥ 15 mg/100 ml in association with the RSV infection was seen more frequently in infants who had higher lgM levels in their acute sera than in infants who had lower levels.

(Arch J Dis Child 131:145-148, 1977)

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