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March 1977

The Return of Boston Exanthem: Echovirus 16 Infections in 1974

Author Affiliations

From the Department of Pediatrics, University of Rochester, Rochester, NY (Dr Hall); UCLA, Los Angeles (Drs Cherry and Winter); the Department of Preventive Medicine, University of Wisconsin; the Virus Section, Wisconsin State Laboratory of Hygiene, Madison, Wise (Dr Hatch); and the Enteric Virology Branch, Center for Disease Control, Atlanta (Mr Nelson).

Am J Dis Child. 1977;131(3):323-326. doi:10.1001/archpedi.1977.02120160077014

• Although the "Boston exanthem" has been seen rarely over the past 20 years, in the summer of 1974 we identified ten children, aged 1 week to 7 years with echovirus 16 infections. Seven of the children had rashes, and in four, the illnesses suggested roseola infantum. Five of these children were neonates, all with illnesses severe enough to mimic sepsis. In addition, information obtained on echovirus 16 isolations occurring in 1974 elsewhere in the country showed an additional 27 isolations from eight states. It is postulated that more outbreaks of the Boston exanthem or other echovirus 16 illnesses will appear during the next several years, before the virus again "disappears."

(Am J Dis Child 131:323-326, 1977)

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