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July 1977

Monocytosis in Congenital Syphilis

Author Affiliations

From the Department of Pediatrics, Long Island Jewish-Hillside Medical Center and Queens Hospital Center Affiliation, and the School of Medicine of the Health Sciences Center, State University of New York at Stony Brook.

Am J Dis Child. 1977;131(7):782-783. doi:10.1001/archpedi.1977.02120200064013

• We evaluated hematological findings, with special reference to the monocyte count, in ten infants with congenital syphilis. One patient had a monocytic leukemoid reaction and eight had absolute monocyte counts considerably higher than normal control infants. Monocytes appear to be an essential participant in the cellular reaction to treponema pallidum. To our knowledge, this is the first report of a monocytic leukemoid reaction in congenital syphilis.

(Am J Dis Child 131:782-783, 1977)