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September 1978

Consumptive Coagulopathy: A Complication of Therapy of Solid Tumors in Childhood

Author Affiliations

From the Department of Pediatrics, State University Hospital, Upstate Medical Center, Syracuse, NY.

Am J Dis Child. 1978;132(9):870-872. doi:10.1001/archpedi.1978.02120340046008

• The association of consumptive coagulopathy and malignancy is thought to be rare in pediatrics. In one patient with Ewing's sarcoma and in two with rhabdomyosarcoma consumptive coagulopathy developed in the presence of either diffuse metastatic disease or an extensive primary tumor. The coagulopathy was a major clinical problem, developing within five days of the onset of chemotherapy. Resolution coincided with the clinical response of the tumor.

(Am J Dis Child 132:870-872, 1978)

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