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February 1979

Congenital Hypopituitarism in Female Infants: Its Association With Hypoglycemia and Hypothyroidism

Author Affiliations

From the Section of Pediatric Endocrinology, Departments of Pediatrics (Drs Kauschansky and Genel) and Pathology (Dr Smith), Yale University School of Medicine and Yale-New Haven Hospital, New Haven, Conn.

Am J Dis Child. 1979;133(2):165-169. doi:10.1001/archpedi.1979.02130020057011

• Congenital hypopituitarism was found in two female infants who had profound hypoglycemia and hypothyroidism. In both infants, death occurred despite recognition of the disorder and institution of appropriate therapy. Autopsy findings showed an absent pituitary gland and sella turcica, with hypoplastic adrenal and thyroid glands, and ovaries in one case, and pituitary gland aplasia with absent thyroid and right adrenal glands plus a hypoplastic left adrenal gland in the other case.

(Am J Dis Child 133:165-169, 1979)