Sir.—Konvolinka and Steward (Am J Dis Child 132:903-905, 1978) describe a patient with pyloric atresia and report 81 cases in the medical literature. Although they do not discuss the possible recurrence in siblings, Tan and Murugasu1 (authors' reference 24) considered their report of affected siblings the first in the literature. Actually, there are at least five other families,2 leading the authors of one article3 to suggest the condition is inherited in an autosomal recessive manner. Presumably, α-fetoprotein levels would be elevated in the amniotic fluid of succeeding affected siblings, which suggests the possibility of prenatal diagnosis.4
SZALAY GC. Familial Pyloric Atresia. Am J Dis Child. 1979;133(2):221. doi:10.1001/archpedi.1979.02130020113026
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