• A 5-year-old girl was discovered to have an abnormal karyotype with a translocation involving the Y chromosome. The primary complaint was slight physical growth retardation. Cytogenetic and endocrinologic evaluations were performed. The chromosomal complement exhibited a mosaicism: 45,X,t(Y;18)(q11;p11)/45,X0. The gonads of this patient were typical streaks containing no ova or follicles. A gonadoblastoma was present bilaterally.
(Am J Dis Child 133:277-282, 1979)
Khodr GS, Cadena GD, Ong TC, Siler-Khodr TM. Y-Autosome Translocation, Gonadal Dysgenesis, and Gonadoblastoma. Am J Dis Child. 1979;133(3):277–282. doi:10.1001/archpedi.1979.02130030053009
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