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March 1979


Author Affiliations

Member State of Illinois Immunization Advisory Committee 2315 E 93rd St Chicago, IL 60617

Am J Dis Child. 1979;133(3):332. doi:10.1001/archpedi.1979.02130030108025

Sir.—The article by Dr Biedel in the Journal (132:678-680, 1978), "Recurrent Mumps Parotitis Following Natural Infection and Immunization," is of particular interest to pediatricians and to members of advisory committees on immunization procedures. If mumps infection can reoccur (despite a substantial rise in specific antibody levels) in children who have received mumps vaccine or who have had clinical mumps, should children be given a booster dose of mumps virus vaccine at the time of exposure or before puberty (especially boys)?

However, Zollar and Mufson1 in 1970 reported that parainfluenza type 3 virus infection can simulate clinical mumps and result also in a rise in serum antibody levels to both parainfluenza type 3 and mumps viruses. Also, as Dr Biedel has noted, other viruses have been reported as a cause of infectious parotitis.

Dr Biedel did not obtain viral cultures in his patients, and the only serum antibody studies

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