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May 1979

Radiological Case of the Month

Author Affiliations

From the Department of Radiology, New York University Medical Center, New York.

Am J Dis Child. 1979;133(5):545-546. doi:10.1001/archpedi.1979.02130050089018

Case History.—A 4-year-old girl was well until eight months prior to admission, when she had a short febrile illness with diarrhea. She was treated for one week with oral chloramphenicol (dose is unknown). Two months later, the same symptoms recurred and she again was given oral chloramphenicol. Subsequently, the patient was noted to have ecchymoses on her face and trunk. A diagnosis of pancytopenia was made and the patient was hospitalized at another institution, where she was treated with androgens and corticosteroids.

Physical examination on transfer to New York University Medical Center, New York, revealed a cushingoid girl, with diffuse ecchymoses of her face and trunk. She was febrile to 40 °C. The results of remainder of the examination were unremarkable.

The patient's laboratory findings included the following values: hematocrit, 20%; WBC, 2,300/cu mm; lymphocytes, 99%; and an absence of platelets and reticulocytes. Treatment at New York University

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