• Plasma immunoreactive prostaglandin A (iPGA) values were determined for 14 premature infants before and after 48 hours of phototherapy and in a control group of six age-matched premature infants. At 4 to 8 days of life, the infants who had received phototherapy for 48 hours had significantly lower iPGA values compared with controls. At 2 to 3 days of life, four infants with a clinically apparent patent ductus arteriosus were found to have significantly elevated iPGA values compared with controls. After 48 hours of phototherapy, these infants likewise had a significant decrease in iPGA values compared with controls; in all four infants, the ductus closed spontaneously. Phototherapy is an effective method for decreasing plasma iPGA values in premature infants.
(Am J Dis Child 133:625-627, 1979)
Aplin CE, Brouhard BH, Cunningham RJ, Richardson CJ. Phototherapy and Plasma Immunoreactive Prostaglandin A Values: Its Effect in Premature Infants. Am J Dis Child. 1979;133(6):625–627. doi:10.1001/archpedi.1979.02130060065014
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