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Article
June 1979

Recurrent Hyperglycemia Associated With Sepsis in a Neonate

Author Affiliations

3015 Brownsboro Rd Louisville, KY 40206; University of Pennsylvania and Pennsylvania Hospital Philadelphia, PA 19107

Am J Dis Child. 1979;133(6):645-646. doi:10.1001/archpedi.1979.02130060085020
Abstract

Sepsis is usually included in the differential diagnosis of neonatal hypoglycemia. It is not generally thought to be associated with neonatal hyperglycemia. We report a low birth weight infant who twice manifested severe hyperglycemia in association with Escherichia coli sepsis.

Report of a Case.—A 1.1-kg female infant was born at 26 weeks of gestation to a gravida 5, para 3, abortus 1 woman. The infant experienced initial respiratory distress, but never required more than 35% oxygen. However, she had frequent episodes of apnea. On the first day of life, theophylline ethylenediamine was given in a dose of 2 mg/kg of body weight every six hours; later, the dose was doubled. By the sixth day of life, the baby was doing well in room air. During the next 14 days, the theophylline dose was reduced and then discontinued. Blood glucose levels obtained every three to four days were normal. After

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