[Skip to Navigation]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address Please contact the publisher to request reinstatement.
June 1979

Endoscopic Retrograde Cholangiopancreatography in the Diagnosis of Extrahepatic Biliary Atresia

Author Affiliations

Division of Liver Diseases and Division of Gastroenterology Department of Medicine The Mount Sinai Hospital and The Mount Sinai School of Medicine New York, NY 10029

Am J Dis Child. 1979;133(6):647-649. doi:10.1001/archpedi.1979.02130060087022

In the evaluation of jaundice in infancy, the differentiation between neonatal hepatitis and biliary atresia may be difficult since there is considerable overlap in the clinical features and the liver biopsy findings. Visualization of the biliary system is desirable and may be diagnostic. This has been accomplished in most cases by operative cholangiography. We report preoperative confirmation of the diagnosis of extrahepatic biliary atresia by endoscopic retrograde cholangiopancreatography (ERCP) in a 4-month-old infant.

Report of a Case.—A 3-week-old female infant, the product of an uncomplicated pregnancy and full-term delivery, was noted to be jaundiced. Laboratory values at five weeks included the following: total serum bilirubin, 9.8 mg/dL; direct bilirubin, 2.5 mg/dL; SGOT, 70 IU/L; and SGPT, 50 IU/L. A liver biopsy performed at ten weeks was interpreted as showing "chronic active hepatitis" and the child was treated with corticosteroids.

One month later, the infant was taken to New York