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Article
November 1979

Cytomegalovirus Syndrome

Author Affiliations

Massachusetts General Hospital Fruit St Boston, MA 02114

Am J Dis Child. 1979;133(11):1204. doi:10.1001/archpedi.1979.02130110112032
Abstract

Sir.—Dr Hanshaw's "Marginal Comment" (Journal 133:475-476, 1979) on Dr Roberta Ballard et al's article "Acquired Cytomegalovirus Infection in Preterm Infants" (Journal 133:481-485, 1979) was entitled, "A New Cytomegalovirus Syndrome?" I must point out that that syndrome was described in a report that appeared in 1957.1 An analysis of the cases reviewed lead me to the conclusion that there were three syndromes associated with the disease, one of which was commonly characterized by chronic respiratory disease in infants beyond the newborn period. Those infants were premature and died after the neonatal period, and on postmortem examination were shown to have had interstitial pneumonitis. Therefore, I believe the syndrome is neither new nor newly described, though clearly Ballard et al contributed significantly to both its definition and understanding by their serologically and virologically complemented clinical studies, as had Kumar et al2 and Whitley et al3 earlier. I realize

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