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December 1979

Infant Botulism

Author Affiliations

Departments of Neurology and Pediatrics University of New Mexico Medical Center Albuquerque, NM 87131

Am J Dis Child. 1979;133(12):1288. doi:10.1001/archpedi.1979.02130120080021

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Sir.—Johnson, Clay, and Arnon presented an excellent review of infant botulism in the Journal (133:586-593, 1979). In it, the authors mentioned that eight of their infants had electromyograms (EMGs) performed. On EMG, none showed enhancement of amplitude on repetitive stimulation (at 20 cps), although two of the four tested showed posttetanic facilitation.

In July 1978, we encountered two cases of infant botulism. Both were male, one was 1 month of age (case 1) and the other 5 months of age (case 2). Both first had constipation, followed in several days by hypotonia, paresis, ptosis and poor suck. Clostridium botulinum, type A, was grown from cultures of the stools of these infants. The infants made uneventful recoveries with supportive care. The EMGs were performed in case 1 on the 14th day after onset of weakness and in case 2 on the 15th day after onset of weakness. In both infants,

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