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January 1980

Severe Neonatal Chlamydial Pneumonitis

Author Affiliations

Pediatric Intensive Care Unit Chaim Sheba Medical Center Tel Hashomer, Israel and; Dr Efraim National Reference Center for Treponematosis University of Tel Aviv Tel Aviv

Am J Dis Child. 1980;134(1):89-91. doi:10.1001/archpedi.1980.02130130071023

Chlamydia are bacteria-like obligatory intracellular parasites. Although they were considered once to be large viruses, they differ from the viruses in having two nucleic acids and in having a discrete cell wall. They do resemble viruses only in the obligatory intracellular nature of their parasitism.1.2

A number of human diseases are caused by Chlamydia. Recent studies have shown that chlamydial infection in the newborn is associated with a pneumonia syndrome that is characterized by an afebrile course, chronic diffuse lung involvement, tachypnea, and elevated serum IgG and IgM levels.3-5

In the 2-week-old infant with severe pneumonitis who is to be described, C trachomatis was isolated from tracheal aspirates as well as from her mother's cervix.

Report of a Case.—A 4,100-g term female infant was born to a 30-year-old mother, after a normal pregnancy, labor, and delivery. There was no maternal history of conjunctivitis, or of respiratory

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