Spontaneous rupture of the spleen is a rare complication in patients with acute leukemia.1-8 In most of the patients diagnosis has been made postmortem, though successful removal of the spleen has been accomplished in a few. Recently, we encountered a case of acute T-cell leukemia in which intraperitoneal bleeding and shock were due to splenic rupture. The patient's condition was managed successfully without surgical intervention.
Report of a Case.—A 13-year-old boy was admitted to Children's Hospital of Michigan, Detroit, on June 14, 1978, with a two-week history of mild difficulty in breathing, generalized petechiae, prominent bilateral cervical adenopathy, and hepatomegaly (5 cm) and splenomegaly (7 cm). The following laboratory values were reported: hemoglobin, 14.2 g/dL; WBCs, 174,000/cu mm, with 90% lymphoblasts; and platelets, 28,000/cu mm. Chest roentgenogram showed an enlarged thymus. Bone marrow examination confirmed the diagnosis of acute lymphoblastic leukemia, and the leukemic blasts formed spontaneous rosettes
DUSHYANT T. SOORYA, YADDANAPUDI RAVINDRANATH, ARVIN PHILIPPART, Bryce Alpern, Donnell Thomas. Spontaneous Splenic Rupture in Acute Lymphoblastic Leukemia: Successful Nonoperative Management. Am J Dis Child. 1980;134(2):201–202. doi:10.1001/archpedi.1980.02130140071019