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May 1980

Eye Involvement in Anaphylactoid Purpura

Author Affiliations

Department of Pediatrics; Section on Ophthalmology Department of Surgery Bowman Gray School of Medicine Winston-Salem, NC 27103

Am J Dis Child. 1980;134(5):524-525. doi:10.1001/archpedi.1980.02130170074027

We have recently observed a patient with an unusually protracted course of anaphylactoid purpura in whom recurrent eye involvement was an unusual feature. Various types of CNS involvement have been uncommonly reported in anaphylactoid purpura.1-3 However, we have been unable to find a report of recurrent and symptomatic eye involvement in anaphylactoid purpura.

Report of a Case.—A 14-year-old girl had acute multiple joint involvement with swelling of her knees, ankles, and right wrist. At the same time, results of a urinalysis showed microscopic hematuria. Approximately two weeks after the onset of her joint symptoms, numerous small 1- to 2-mm macular lesions were noted on the lower extremities and buttocks. Two weeks later, she had crampy abdominal pain, melena, and gross blood in her stools.

Physical examination at that time showed a pale, irritable girl in moderate distress. A diffuse maculopapular rash was noted, involving the lower extremities and