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July 1980

Acute Glomerulonephritis and Streptococcal Skin Lesions in Eskimo Children

Author Affiliations

From the Alaska Investigations Division, Bureau of Epidemiology, Center for Disease Control, Anchorage (Drs Margolis, Lum, and Bender, and Mss Elliott and Harpster); Public Health Service Alaska Native Hospital, Alaska Area Native Health Service, Bethel (Dr Lum); and the Maternal and Child Health Care Branch, Alaska Area Native Health Service, Anchorage (Ms Fitzgerald).

Am J Dis Child. 1980;134(7):681-685. doi:10.1001/archpedi.1980.02130190049013

• Poststreptococcal acute glomerulonephritis often follows impetigo and can occur in epidemics. From 1975 through 1977, an epidemic of poststreptococcal acute glomerulonephritis occurred in Alaska. Fifty children required hospitalization, while 25 less seriously ill children were treated as outpatients. Sixty-seven percent of these 75 children had direct evidence of recent skin infections. Serotypes 49-14 and NT-14 were the most common streptococcal isolates. In villages in the epidemic area, approximately 15% of children had impetigo and more than 60% of lesions cultured were positive for group A streptococci. Impetigo rates in the epidemic area were similar to those found in nonepidemic areas. However, the introduction of the nephritogenic streptococcal serotypes not recently present in this population apparently led to the development of the epidemic.

(Am J Dis Child 134:681-685, 1980)