Pseudohypoparathyroidism is a disorder characterized by typical somatic features, hypocalcemia, hyperphosphatemia, elevated circulating levels of parathormone (PTH), and unresponsiveness to parathyroid injection.1,2 Although the clinical and roentgenographic features of this condition have been the subject of various reports and reviews,1,3 abnormalities of the spine are rarely described. In this report, we present a patient with pseudohypoparathyroidism who had spinal cord compression owing to bony narrowing of the spinal canal.
Report of a Case.—A 3-year 10-month-old boy was evaluated for short stature and developmental delay. His birth history and medical history were unremarkable. There was no history of seizures or tetany. The mother was found to have pseudo-pseudohypoparathyroidism based on clinical and biochemical features and confirmed by normal urinary adenosine 3′:5′-cyclic phosphate (cAMP) response to parathyroid injection.2 He was short (height age, 1 year and 10 months) and obese, and he had rounded facies and small and broad hands with stubby
ANITA CAVALLO, WALTER J. MEYER, JOHN B. BODENSTEINER, ANDREW L. CHESSON. Spinal Cord Compression: An Unusual Manifestation of Pseudohypoparathyroidism. Am J Dis Child. 1980;134(7):706–707. doi:10.1001/archpedi.1980.02130190072020