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August 1980

Pediatric Neuromuscular Diseases

Author Affiliations

Division of Child Neurology Boston City Hospital 818 Harrison Ave Boston, MA 02118

Am J Dis Child. 1980;134(8):804. doi:10.1001/archpedi.1980.02130200072031

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.


Pediatric Neuromuscular Disease is intended to present a systematic approach to the child with neuromuscular disorders. The first chapter reviews neuromuscular anatomy, history taking and physical examination, normal maturation of the motor system, and central and peripheral hypotonias. The second chapter reviews embryonic development and ultrastructure of muscles and the diagnostic usefulness of electromyography, nerve-conduction studies, and muscle biopsy. Next, the pediatric neuromuscular diseases are classified according to the anatomic location of their chief pathologic conditions. Single chapters are allotted to motor neuron disease, disorders of nerve roots and peripheral nerves, and diseases of the neuromuscular junction. The final three chapters are devoted to muscle disease, discussed under the categories of progressive muscular dystrophies, unusual myopathies and congenital defects of muscle, and myositis.

The detailed clinical descriptions and discussions of differential diagnosis make this a helpful book for the student or clinician in pediatric neuromuscular disease. The more recently described

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