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September 1980

Pregnancy Metabolism, Diabetes and the Fetus: Ciba Foundation Symposium No. 63 (New Series)

Author Affiliations

Strong Memorial Medical Center 601 Elmwood Ave Rochester, NY 14642

Am J Dis Child. 1980;134(9):904. doi:10.1001/archpedi.1980.02130210080031

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This book is an excellent compendium on maternal and fetal metabolism, their interrelationships, and the resultant perturbations on this unit caused by diabetes. There are 13 chapters, all of which are followed by a discussion, written by 26 well-recognized authorities in this field. Initial sections focus on normal maternal metabolism, transplacental substrate fluxes, and normal fetal nutrition. These chapters provide a smooth transition to two highly culled topics among many possibilities, namely, the hormonal regulation and induction of hepatic and placental enzymes. Remaining sections cover altered fetal metabolism secondary to maternal diabetes and its eventuality, in particular, in perinatal morbidity and congenital malformations. Each chapter and its discussion are replete with information, and all are well referenced and well written—despite the confusing use of pregnancy as an adjective in the book's title. The ensuing interchange of ideas by the collaborators is delightful, provocative, seemingly unedited, and occasionally vitriolic. I enjoyed