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September 1980

Liver Disorders in Childhood

Author Affiliations

Children's Hospital of Philadelphia 34th St and Civic Center Blvd Philadelphia, PA 19104

Am J Dis Child. 1980;134(9):907. doi:10.1001/archpedi.1980.02130210083037

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.


This is one of the first texts entirely devoted to pediatric liver disease. Written by Dr Mowat, a pediatrician and pediatric gastroenterologist, it combines a vast clinical experience with a format that is organized to assist the clinician approaching the child who has liver disease. The first few chapters deal exceedingly well with the normal liver of childhood from the standpoints of anatomy, physiology, and assessment of liver size. Though not exhaustive with regard to pathophysiology, the chapters are well referenced and quite up to date. The sections dealing with conjugated hyperbilirubinemia are complete with good tables to assist the physician in differential diagnosis. A discussion of the infectious and metabolic causes of liver disease together with the treatment of cirrhosis and portal hypertension relates to the pediatric experience and, thus, clearly fills a gap in current textbooks devoted to liver disease. The section on diagnostic modalities, particularly the use