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October 1980

Human Milk

Author Affiliations

Department of Pediatrics Jewish Hospital and Medical Center of Brooklyn State University of New York/Downstate Medical Center 555 Prospect PI Brooklyn, NY 11238

Am J Dis Child. 1980;134(10):1002. doi:10.1001/archpedi.1980.02130220078037

Sir.—The results and conclusion of a recent report on cells and aqueous component of human milk by Gene L. France and associates require comment (Journal 134:147-152, 1980).

It has been documented that human milk cells are functionally competent.1,2 They are capable of ingestion and killing of microorganisms.1,2 The aqueous component, on the other hand, is complementary to the cells in providing opsonins.2 In addition, we have demonstrated that the milk cells are capable of reducing nitro blue tetrazolium.3,4 Using the colostric leukocytes, this has been confirmed by France et al. The latter investigators, however, have reported a lack of chemotactic factor or factors in aqueous milk and a lack of chemotactic migration capacity by milk cells. We recently determined (using a modified Boyden's technique3,4) that milk cells obtained from 20 lactating women were capable of chemotactic migration in response to chemotactic factor or factors,

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