• The recovery time of adrenocortical function was studied in 13 children receiving intermittent high-dosage glucocorticoid therapy (prednisone, 2 mg/kg/day) for one month out of every four months as treatment for acute leukemia. The data indicate that the adrenal gland's ability to respond to stress recovers rapidly from such treatment. The results of our study clearly show that routine supplementation with glucocorticoid therapy in these patients during periods of clinical stress occurring later than nine days after glucocorticoid therapy is not warranted.
(Am J Dis Child 1981;135:790-792)
Lightner ES, Johnson H, Corrigan JJ. Rapid Adrenocortical Recovery After Short-term Glucocorticoid Therapy. Am J Dis Child. 1981;135(9):790–792. doi:10.1001/archpedi.1981.02130330002002
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: