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May 1982

Infants With Bronchopulmonary Dysplasia: Growth Pattern and Neurologic and Developmental Outcome

Author Affiliations

From the Department of Pediatrics, Women and Infants Hospital of Rhode Island, and Section of Reproductive and Developmental Medicine, Brown University Program in Medicine, Providence, RI. Dr Bell is now with the Department of Pediatrics, University of Iowa, Iowa City.

Am J Dis Child. 1982;136(5):443-447. doi:10.1001/archpedi.1982.03970410061015

• We evaluated neurodevelopmental and growth outcomes of low-birth-weight infants with bronchopulmonary dysplasia (BPD). Twenty-six cases of BPD (group A) were diagnosed from 244 neonatal survivors with a low birth weight (≤ 1,500 g) born in 1975, 1976, and 1977. During the same period, BPD did not develop in eight infants with a comparable neonatal course (group B) (received oxygen therapy ≥ 21 days). Twenty-five infants who received O2 therapy five or fewer days had a mild clinical course and were considered controls (group C). The BPD infants suffered more asphyxia, respiratory distress syndrome, acidosis, and longer parenteral alimentation and hospitalization than group C infants. Compared with groups B and C, the BPD infants had more respiratory morbidities at 4 and 12 months (P <.005) and more severe neurodevelopmental sequelae at 2 years.

(Am J Dis Child 1982;136:443-447)