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June 1982

Transient Neonatal Pustular Melanosis

Author Affiliations

From the Department of Neonatology (Drs Merlob and Reisner) and the Pediatric Dermatology Unit (Dr Metzker), Beilinson Medical Center, Petah Tiqva, Israel and the Tel Aviv (Israel) University Sackler School of Medicine (Drs Merlob, Metzker, and Reisner).

Am J Dis Child. 1982;136(6):521-522. doi:10.1001/archpedi.1982.03970420045009

• Transient neonatal pustular melanosis was diagnosed in 13 of 5,267 infants examined over a period of 17 months, representing an incidence of 0.24%. The skin eruption was always present at birth and developed within a few days from pustules to a round, brownish crust, which could easily be detached. Histological examination of two biopsy specimens obtained at the age of 4 days showed hyperkeratosis with keratotic plugs and a crust of leukocytes, but no increased melanin.

(Am J Dis Child 1982;136:521-522)