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August 1982

Echovirus 3 Infection Associated With Anicteric Hepatitis

Author Affiliations

Nassau County Medical Center East Meadow, NY State University of New York Stony Brook, NY; Nassau County Medical Center East Meadow, NY

Am J Dis Child. 1982;136(8):744-745. doi:10.1001/archpedi.1982.03970440088028

Echovirus type 3 has been associated with a variety of clinical syndromes, including aseptic meningitis, upper respiratory tract infection, exanthem, paralysis, myocarditis, pericarditis, Reye's syndrome, and severe neonatal infection.1

This article describes a young infant with suspected sepsis who had anicteric hepatitis during an echovirus 3 infection. We wish to make clinicians aware of this association, which to our knowledge has not been reported previously.

Report of a Case.—A 2-month-old female infant was admitted to the Nassau County (New York) Medical Center in September 1981, for suspected sepsis. The infant had been well until the day of admission, when she became irritable and slept more than usual. In the evening her temperature rose to 39.8 °C, for which she was given one half of a baby aspirin tablet. A 15-month-old brother had had a three-day febrile illness with rash two weeks prior to our patient's admission. Perinatal history