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September 1983

Delayed Cerebral Development in Twins With Congenital Hyperthyroidism

Author Affiliations

From the Neonatology Section, Department of Pediatrics, East Carolina University School of Medicine, Greenville, NC.

Am J Dis Child. 1983;137(9):842-845. doi:10.1001/archpedi.1983.02140350020006

• Twins had congenital hyperthyroidism and delayed cerebral development manifested as ventriculomegaly, increased space in the interhemispheric fissure, and an exaggerated gyral pattern on cranial computed tomographic scans. At 3½ years of age, both children had delayed development. Fetal and neonatal hyperthyroidism may interfere with normal brain growth and maturation with both neuroanatomic and developmental sequelae.

(Am J Dis Child 1983;137:842-845)

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