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November 1983

Bacterial Meningitis in Older Neonates

Author Affiliations

From the Department of Pediatrics, Division of Infectious Diseases and Immunology, University of Arkansas for Medical Sciences and Arkansas Children's Hospital, Little Rock.

Am J Dis Child. 1983;137(11):1052-1054. doi:10.1001/archpedi.1983.02140370014005

• During a five-year period, 24 patients' conditions (age range, 2 to 6 weeks) were diagnosed, and they were treated for bacterial meningitis. Organisms recovered from the CSF included group B Streptococcus (n = 6), Escherichia coli (n = 5), Listeria monocytogenes (n = 5), Hemophilus influenzae (n = 4), Streptococcus pneumoniae (n = 2), and group D and group A Streptococcus (one each). Initial antimicrobial therapy must include antibiotics that are effective across this spectrum of potential pathogens. Symptoms and signs were often subtle. Six children (25%) experienced major neurologic residua, including five patients (21%) in whom hydrocephalus developed. Ultrasound examination of the head at the end of therapy was an effective technique for early assessment of neurologic sequelae.

(Am J Dis Child 1983;137:1052-1054)