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February 1984

Intraventricular Hemorrhage: Incidence and Outcome in a Population of Very-Low-Birth-Weight Infants

Author Affiliations

From the Departments of Pediatrics (Drs Hawgood and Yu) and Radiology (Dr Spong), Queen Victoria Medical Centre, Melbourne.

Am J Dis Child. 1984;138(2):136-139. doi:10.1001/archpedi.1984.02140400022005

• The incidence, extent, and outcome of germinal matrix hemorrhage-intraventricular hemorrhage (GMH-IVH) were determined with the use of ultrasound and autopsy findings in 100 consecutive infants, with a birth weight of less than 1,500 g. Serial ultrasound examinations once or twice weekly were performed with the use of a portable real-time linear-array scanner. The overall incidence of GMH-IVH was 46%. Twenty infants had grade 1 (GMH), 24 had grade 2 (IVH ± GMH), and two had grade 3 (IVH±GMH with intracerebral hemorrhage) conditions. The mortality in infants with GMH-IVH was 35%, compared with 13% in infants without GMH-IVH. Although 11 (37%) of 30 survivors with GMH-IVH had ventricular dilatation, only two infants required ventriculoperitoneal shunts for progressive hydrocephalus. The incidence of GMH-IVH was increased in outborn infants, in those delivered vaginally, and in those who required mechanical ventilation, bicarbonate therapy, or volume expansion in the first 24 hours. The long-term prognostic significance of the ultrasound findings was unknown and will be determined by follow-up studies.

(AJDC 1984;138:136-139)

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