• A kindred with five affected maternally related male members showed variable phenotypic expression of the X-linked lymphoproliferative syndrome. In one of the children, agammaglobulinemia developed following infectious mononucleosis. His brother had aplastic anemia in infancy and 2½ years later died of overwhelming pneumonia resulting from ornithosis. A third brother died of reticulum cell sarcoma. Two maternally related male cousins died of reticulum cell sarcoma of the neck.
Reuben Steinherz, Yael Levy, Aviva Litwin, Menachem Nitzan, Eva Friedman, Stanley Levin. X-Linked Lymphoproliferative SyndromeA New Kindred With Variable Phenotypic Expression. Am J Dis Child. 1985;139(2):191–193. doi:10.1001/archpedi.1985.02140040093036