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Article
March 1985

Fatal Gastroenteritis Associated With Coronaviruslike Particles

Author Affiliations

From the Departments of Pediatrics (Dr Rettig) and Pathology (Dr Altshuler), College of Medicine, University of Oklahoma Health Sciences Center; and Oklahoma Children's Memorial Hospital (Drs Rettig and Altshuler), Oklahoma City.

Am J Dis Child. 1985;139(3):245-248. doi:10.1001/archpedi.1985.02140050039017
Abstract

• The role of human enteric coronaviruses in infantile gastroenteritis is controversial. We detected coronavirus-like particles in the intestinal contents and within the epithelial cells of the ileum in a 15-month-old infant who had postmortem evidence of severe enteritis. Ultrastructural findings consistent with in vivo coronavirus replication in the human small intestine support a causative role for this agent in gastroenteritis.

(AJDC 1985;139:245-248)

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