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This text was conceived as a selection of topics in neonatal neurology in which there have been recent rapid advances in knowledge. Several topics are discussed by more than one contributor. The book appears to be targeted mainly toward neurologists involved in the care of newborns, although neonatologists will certainly appreciate many of the topics.
The varieties of neonatal seizures are described under three topics: the diagnosis and management of hypoxiaischemia, the electroencephalogram (EEG) in the neonatal period, and neonatal seizures. In the latter, the important role of the EEG in the identification of subtle seizures is stressed, and it is emphasized that stereotyped movements and generalized parasympathetic discharges are common release phenomena and rarely represent true seizures, as reflected by EEG ictal activity.
Perinatal cerebral hypoxia-ischemia is discussed as two topics. The section on pathogenesis and neuropathology focuses on traditional pathologic concepts and on more recent ideas of abnormal