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October 1986

Lorazepam in the Treatment of Refractory Neonatal SeizuresA Pilot Study

Am J Dis Child. 1986;140(10):1042-1044. doi:10.1001/archpedi.1986.02140240088032

• Seven neonatal patients with severe seizures unresponsive to conventional anticonvulsant therapy were treated with lorazepam. Immediate cessation of seizure activity occurred in all patients within five minutes. Although seizures recurred in two infants eight hours later, frequency and severity diminished. There were no apparent significant side effects attributed to the medication.

(AJDC 1986;140:1042-1044)