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May 1987

Nonimmune Hydrops Fetalis in Noonan's Syndrome-Reply

Author Affiliations

Division of Genetic, Metabolic, and Developmental Disorders
Division of Neonatology Children's Hospital of Michigan 3901 Beaubien Detroit, MI 48201

Am J Dis Child. 1987;141(5):479. doi:10.1001/archpedi.1987.04460050021017

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In Reply.—We thank Dr Oudesluys-Murphy for reporting this mild case of hydrops fetalis in Noonan's syndrome that corroborates our observation. The incidence of nonimmune hydrops without congenital heart failure in Noonan's syndrome is unknown, and, hence, its significance in relation to the severity of the other manifestations of the syndrome remains to be determined.

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