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May 1987

Investigation of Issues in GrowthA Vital Concern for Pediatrics

Am J Dis Child. 1987;141(5):485. doi:10.1001/archpedi.1987.04460050027022

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If pediatrics has any basic science that it can claim as unique, it is growth and development. This issue contains articles dedicated to that theme, from basic studies in growth phenomena to long-term growth characteristics in children with chronic diseases, growth-limiting treatment, and organ transplantation. In addition to these original articles, there is a stateof-the-art review of regulation of growth in children with chronic illness.

See also pp 489, 502, 511, 516, 520, 531, 535, 541, 547, 550, 553, and 565.

The growth of an individual from two germ cells into a mature, functioning adult is one of nature's remarkable phenomena. Under the guidance of chromosomal direction, cells develop, fuse, and interact with one another; produce proteins, carbohydrates, and lipids within stringent limits; and are integrated into highly complex, functional tissues and organs. When one considers all the adverse influences that can produce aberrations in this process, it is remarkable that most of us

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