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June 1987

Hepatocarcinoma in a Child With the Alagille Syndrome

Am J Dis Child. 1987;141(6):698-700. doi:10.1001/archpedi.1987.04460060114050

• A child with the Alagille syndrome of intrahepatic bile duct paucity developed hepatocarcinoma. Disabling cirrhosis had rendered this child a suitable candidate for transplantation before the discovery of carcinoma. However, the extension of the tumor outside the liver precluded the performance of this potentially life-saving operation. Serial monitoring of the serum μ-fetoprotein concentration may be of value in the early identification of tumors in pediatric candidates for transplantation.

(AJDC 1987;141:698-700)