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August 1987

Typhoid and Paratyphoid Fever in 192 Hospitalized Children in Thailand

Author Affiliations

From the Division of Infectious Disease, Children's Hospital, Bangkok, Thailand (Drs Thisyakorn and Mansuwan); and the Department of Bacteriology, Armed Forces Research Institute of Medical Sciences, Bangkok (Dr Taylor). Dr Thisyakorn is now with Chulalongkorn Hospital, Bangkok.

Am J Dis Child. 1987;141(8):862-865. doi:10.1001/archpedi.1987.04460080048025

• From 1977 to 1984, Salmonella typhi was isolated from 85% and Salmonella paratyphi A was Isolated from 15% of 192 Thai children with enteric fever at children's Hospital, Bangkok. Children with enteric fever presented with sudden onset of fever and gastrointestinal symptoms. Diarrhea occurred in 62% of children with paratyphoid fever and 36% of children with typhoid fever. Rose spots were seen in 15% of patients with typhoid and 7% of patients with paratyphoid fever. There were no deaths. Bronchitis and pneumonia occurring In 11% of patients were the most common complications. Acute hemolysis occurred in 3% of the patients with typhoid fever who had thalassemia or glucose-6-phosphate dehydrogenase deficiency. Chloram-phenicol-resistant S typhi, which accounted for 70% of the isolates in 1977, has since 1982 accounted for less than 2% of isolates.

(AJDC 1987;141:862-865)