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September 1987

The Hazards of Benign(?) Neglect of Elevated Blood Lead Levels-Reply

Author Affiliations

Department of Pediatrics Northwestern University and Children's Memorial Hospital 2300 Children's Plaza Chicago, IL 60614

Am J Dis Child. 1987;141(9):942. doi:10.1001/archpedi.1987.04460090018011

In Reply.—Dr Needleman and colleagues raise many controversial issues in their response. Unfortunately, the important aspects of our study have been overlooked, namely, the fact that data on the natural decline in Pb-B levels for practical purposes exist only in our study (with respect to sample size and length of observation). Finally, while these critics advocate chelation therapy "to permanently reduce blood lead level to less than 1.21 μmol/L (25 μg/dL),"1 they offer no data to suggest that it is even possible to accomplish this in pateints similar to those described in our longitudinal study.

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