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September 1988

Bone Mineral Content in Infants: Which Machine or Which Bone?-Reply

Author Affiliations

Department of Pediatrics
Departments of Pediatrics and Biochemistry Loma Linda University Medical Center Loma Linda, CA 92350

Am J Dis Child. 1988;142(9):919. doi:10.1001/archpedi.1988.02150090017012

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In Reply.—In testing the humerus as a site for BMC measurements, we used the commercially available instrument we had (Norland 278A). We are therefore referring to measurements performed with a specific instrument. We have not performed the study using other instruments, but, as far as we know, this has not been done by others either. If the BMC at the humerus and radius sites were measured by another instrument (eg, Lunar instrument), we believe that our studies would be confirmed by the "more sensitive" instrument.

The coefficient of variation in our article referred to the variability of repositioning, together with the variability between two different investigators. This cannot be compared with the repositioning variability of one investigator, which was apparently the case in the article by Greer et al. In our studies, the coefficient of variation for the measurement, done by one investigator in the postmortem studies, was 3.6%,

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