Sir.—Maternal floor infarction (MFI) is an uncommon placental lesion associated with stillbirth and intrauterine growth retardation, with an apparent high rate of recurrence in subsequent pregnancies.1-3 The condition has been infrequently discussed in the obstetric or pathology literature, and essentially no information is available in pediatric or genetic journals.
Patient Report.—A 690-g male infant was born after a 36-week gestation. His birth length was 31.0 cm, and his head circumference was 26.0 cm. He had first-degree hypospadias, bilateral cryptorchidism, inguinal hernias, and bilateral bridged palmar creases. No other minor or major anomalies and no specific malformation syndrome were identified. Blood IgM levels, cytomegalovirus, herpes virus, and toxoplasmosis titers, and chromosomal analysis results were normal. The placenta weighed 155 g and showed extensive fibrosis on the maternal surface. Microscopic sections of the placenta confirmed the diagnosis of MFI.
The patient's parents are nonconsanguineous and in good health. The
NICKEL RE. Maternal Floor Infarction: An Unusual Cause of Intrauterine Growth Retardation. Am J Dis Child. 1988;142(12):1270–1271. doi:10.1001/archpedi.1988.02150120024020
Customize your JAMA Network experience by selecting one or more topics from the list below.