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March 1989

Home Oxygen Therapy for Chronic Lung Disease in Extremely Low-Birth-Weight Infants

Author Affiliations

From the Eudowood Pediatric Respiratory Science Division (Drs B. Hudak and Loughlin) and the Eudowood Neonatal Pulmonary Division (Drs Allen and M. Hudak), Department of Pediatrics, The Johns Hopkins University School of Medicine, Baltimore, Md.

Am J Dis Child. 1989;143(3):357-360. doi:10.1001/archpedi.1989.02150150115028

• Chronic lung disease that requires prolonged oxygen therapy commonly complicates the recovery of extremely low-birth-weight infants (<1000 g). We report follow-up data through 18.5±0.9 (mean±SEM) months of age in 30 extremely low-birth-weight infants (birth weight, 783±24 g; gestational age, 26.0±0.3 weeks) who were discharged home receiving supplemental oxygen. Oxygen was prescribed to maintain arterial oxygen saturation at 95% or greater. At discharge, postconceptional age was 40.5±0.6 weeks, and weight was 2220±50 g. Duration of home oxygen therapy was 4.5±0.5 months. The mean weight percentile increased from less than 5 to 23 between discharge and the last follow-up. All infants survived; only 6 required hospitalization for acute medical illnesses. We conclude that carefully supervised home oxygen therapy permits the safe early discharge of selected extremely low-birth-weight infants with chronic lung disease.

(AJDC. 1989;143:357-360)

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