[Skip to Navigation]
July 1990

Atrioventricular Canal Without Down Syndrome Associated With Additional Cardiac and Noncardiac Anomalies-Reply

Author Affiliations

PO Box 9600 2300 PC Leiden the Netherlands

Am J Dis Child. 1990;144(7):752. doi:10.1001/archpedi.1990.02150310018016

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.


In Reply.—With great interest we read the observations of Dr Marino and colleagues on concomitant malformations in children with atrioventricular septal defect (AVSD) without Down syndrome. They further corroborate our conclusion that AVSD is most often part of a complex of congenital anomalies. Hopefully, awareness of this phenomenon will increase and its relevance will be recognized. The separate phenotypic anomalies described are rather aspecific and subtle and they will be easily missed in everyday practice. A combination of these peculiarities could possibly form a complex associated with AVSD. Future research will learn whether the term "non-Down AVSD syndrome" is rightly coined.

First Page Preview View Large
First page PDF preview
First page PDF preview
Add or change institution